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Human IL-17 RC Protein, His Tag

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分子別名(Synonym)

国产视频appIL-17 RC,IL-17RC,IL17Rhom,IL-17 receptor C,IL-17RL,ZcytoR14

表達區間及表達系統(Source)

Human IL-17 RC, His Tag (ILC-H5249) is expressed from human 293 cells (HEK293). It contains AA Leu 21 - Ala 454 (Accession # NP_116121.3).

国产视频appPredicted N-terminus: His

蛋白結構(Molecular Characterization)

Online-Res(Leu 21 - Ala 454) NP_116121.3

This protein carries a polyhistidine tag at the N-terminus.

The protein has a calculated MW of 14.7 kDa.

內毒素(Endotoxin)

制劑(Formulation)

国产视频appPlease contact us for detailed information.

Contact us for customized product form or formulation.

重構方法(Reconstitution)

国产视频appPlease see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存儲(Storage)

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

国产视频appThis product is stable after storage at:

  1. -20°C to -70°C for 12 months in lyophilized state;
  2. -70°C for 3 months under sterile conditions after reconstitution.
 

背景(Background)

Interleukin-17 receptor C (IL-17 RC), also known as IL17Rhom, IL-17RL, is the receptor for IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RA. IL-17A activity is inhibited by IL-17RA, IL-17F is inhibited by IL-17RC, and a combination of soluble IL-17RA/IL-17RC receptors is required for inhibition of the IL-17F/IL-17A activity. Furthermore, activation of IL17RC can lead to the induction of expression of inflammatory chemokines and cytokines such as CXCL1.

 

前沿進展

貨號/價格

ILC-H5249-100ug / ¥3000

国产视频appILC-H5249-1mg / ¥19800

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